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Peptide Bioavailability: Advances in Structural Modification and Oral Uptake Mechanisms

by Rawamino | Nov 5, 2025 | Peptides

Introduction Peptides represent an expanding class of biologically active molecules that bridge the gap between small molecules and larger biotherapeutics. Their modular amino acid architecture enables highly selective interactions with receptors, enzymes, and...

Systems Neuropeptides: Mechanistic Axes and Experimental Frameworks for Brain Research

by Rawamino | Nov 5, 2025 | Peptides

Introduction Neural circuits operate through layered codes of ions, metabolites, and peptides that collectively regulate plasticity, stress responses, and circuit homeostasis in experimental preparations. Beyond classical monoamines, neuropeptides signal coordinate...

Molecular Peptide Programs in Tendon Remodeling: Preclinical Mechanisms and Experimental Readouts

by Rawamino | Nov 5, 2025 | Peptides

Introduction Tendons are hierarchically organized collagenous tissues that transmit force from muscle to bone while accommodating repeated mechanical load. In laboratory models, tendon injury typically proceeds through an acute inflammatory phase, a proliferative...

Systems-Level Effects of a Pan-AMPK Activator (OS-01/O304) on Glucose Flux and Microvascular Dynamics in Experimental Models

by Rawamino | Nov 4, 2025 | Peptides

Introduction Cellular energy homeostasis relies on adaptive sensing that reallocates resources when ATP demand outpaces supply. AMP-activated protein kinase (AMPK) coordinates this response by promoting catabolic ATP-generating pathways and tempering ATP-consuming...

Neuropeptidergic Modulators of Central Circuits: Mechanistic Perspectives for 2025

by Rawamino | Nov 4, 2025 | Peptides

Introduction Peptide biology within the central nervous system (CNS) encompasses a diverse repertoire of signaling molecules that operate beyond classical monoamine neurotransmission. Over the past decade, preclinical investigations have mapped peptide-mediated...
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Latest Blog Post

  • Peptide Bioavailability: Advances in Structural Modification and Oral Uptake Mechanisms
  • Systems Neuropeptides: Mechanistic Axes and Experimental Frameworks for Brain Research
  • Molecular Peptide Programs in Tendon Remodeling: Preclinical Mechanisms and Experimental Readouts
  • Systems-Level Effects of a Pan-AMPK Activator (OS-01/O304) on Glucose Flux and Microvascular Dynamics in Experimental Models
  • Neuropeptidergic Modulators of Central Circuits: Mechanistic Perspectives for 2025

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