AOD 9604 - 5MG

AOD 9604 – 5MG

(68 customer reviews)

$50.00

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Discount per Quantity

QuantityDiscountPrice
5 - 85%$47.50
9 +10%$45.00
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Size 5MG
Form Lyophilized powder
Purity 99%
Contents AOD 9604 - 5MG

Scientific Overview of AOD 9604

AOD 9604 is a synthetic peptide fragment originally derived from growth hormone research. It was designed as a modified version of the C-terminal portion of human growth hormone (hGH). Researchers have explored its potential relationship to lipid metabolism and adipose tissue breakdown.

Alternative Names: AOD-9604

Studies and Research Data

AOD 9604 Research on Molecular Structure

Investigations have suggested that only a small segment of the hGH molecule may play a role in lipid regulation. Early work focused on the hGH fragment 177–191, which was later modified by adding a tyrosine residue, leading to the development of AOD 9604. Reports indicate that the fragment does not appear to interact with hGH receptors, which may influence its distinct properties compared to the full hormone.

Investigations into Metabolic Pathways

Some murine studies suggest that AOD 9604 may encourage lipolytic processes in adipose tissues. Experimental findings indicate that the compound may trigger cellular mechanisms that release fatty acids from fat stores without significantly altering insulin or IGF-1 levels. Additional work has proposed a possible connection to lipase activity, which could influence fat storage dynamics.

AOD 9604 Studies on Obesity Models

In obese murine models, both growth hormone and AOD 9604 have been linked to reductions in body fat mass, though the outcomes appeared different in lean models. Researchers reported that growth hormone may increase lean body mass, while AOD 9604 did not appear to show the same trend. In clinical contexts, AOD 9604 has also been evaluated in obesity-related trials, where ongoing work continues to assess its potential role.

Research on Cardiovascular Function

Because obesity is strongly associated with cardiovascular strain, investigators have speculated that AOD 9604’s influence on adipose reduction may indirectly affect cardiac performance. These pathways may involve both receptor-dependent and receptor-independent mechanisms related to metabolic regulation.

AOD 9604 Exploration in Joint Research

Animal research has suggested that AOD 9604 might influence cartilage metabolism. Rabbit models of osteoarthritis have been examined, with observations pointing to potential changes in joint mobility and cartilage condition. These findings remain preliminary and require further investigation.

Conclusion

Research on AOD 9604 has focused on its relationship to lipid metabolism, obesity models, and metabolic pathways. Findings suggest it may operate differently than growth hormone, particularly in relation to receptor interaction and lean body mass. While animal and early human studies indicate possible roles in adipose regulation, the compound remains under investigation across several scientific fields.

References

  1. Bray, G. A., & Greenway, F. L. (2007). Pharmacological treatment of the overweight patient. Pharmacological Reviews, 59(2), 151–184. https://doi.org/10.1124/pr.59.2.2
  2. Ng, F. M., Jiang, W. J., Gianello, R., Pitt, S., & Roupas, P. (2000). Molecular and cellular actions of a structural domain of human growth hormone (AOD9401) on lipid metabolism in Zucker fatty rats. Journal of Molecular Endocrinology, 25(3), 287–298.
  3. Cox, H. D., Smeal, S. J., Hughes, C. M., Cox, J. E., & Eichner, D. (2015). Detection and in vitro metabolism of AOD 9604. Drug Testing and Analysis, 7(1), 31–38. https://doi.org/10.1002/dta.1715
  4. Kwon, D. R., & Park, G. Y. (2015). Effect of Intra-articular Injection of AOD 9604 with or without Hyaluronic Acid in Rabbit Osteoarthritis Model. Annals of Clinical and Laboratory Science, 45(4), 426–432.
  5. Heffernan, M., Summers, R. J., Thorburn, A., Ogru, E., Gianello, R., Jiang, W. J., & Ng, F. M. (2001). The effects of human GH and its lipolytic fragment (AOD 9604) on lipid metabolism following chronic treatment in obese mice and beta(3)-AR knock-out mice. Endocrinology, 142(12), 5182–5189. https://doi.org/10.1210/endo.142.12.8522
  6. Ng, F. M., Sun, J., Sharma, L., Libinaka, R., Jiang, W. J., & Gianello, R. (2000). Metabolic studies of a synthetic lipolytic domain (AOD 9604) of human growth hormone. Hormone Research, 53(6), 274–278. https://doi.org/10.1159/000053183
  7. Heffernan, M. A., Thorburn, A. W., Fam, B., Summers, R., Conway-Campbell, B., Waters, M. J., & Ng, F. M. (2001). Increase of fat oxidation and weight loss in obese mice caused by chronic treatment with human growth hormone or a modified C-terminal fragment. International Journal of Obesity, 25(10), 1442–1449. https://doi.org/10.1038/sj.ijo.0801740
  8. Kopchick, J. J., Berryman, D. E., Puri, V., Lee, K. Y., & Jorgensen, J. O. (2020). The effects of growth hormone on adipose tissue: old observations, new mechanisms. Nature Reviews Endocrinology, 16(3), 135-146.

Disclaimer:
The products mentioned are intended solely for laboratory research and in-vitro experimentation. They are not approved for human or animal use of any kind. All details provided are for educational purposes only. By purchasing from this site, you agree to comply with our Terms and Conditions.

Certificate of Analysis - AOD 9604

High Performance Liquid Chromatography - AOD 9604

Mass Spectrometry - AOD 9604

68 reviews for AOD 9604 – 5MG

  1. James101 –

    Good peptide

  2. James10 –

  3. Susan D. –

  4. MatthewC11 –

  5. WendyR –

    Good experience overall, would recommend.

  6. Natasha1 –

    Great product

  7. Natasha133 –

  8. ablevins –

    Excelente servicio y entrega rápida.

  9. DawnKneller –

    Happy with the order, but shipping costs are high.

  10. James6 –

    Stable results

  11. KathyQui12 –

    How do we know how to use?

  12. Squidward23 –

    Great supplier, dependable and fast.

  13. Jennifer15 –

    Boomshakalaka

  14. Jose R –

    muy buena calidad, llegó rápido.

  15. Edward43 –

    Love raw amino, thank you

  16. JennyJJ3 –

    fine but labeling wasn’t very clear

  17. snydervalerie –

    Worked for me.

  18. RachelS –

    Powerful peptide thank you

  19. DavidAckerman1 –

    Product arrived exactly as expected, well packaged. Very reliable supplier, always consistent. Good experience overall, would recommend.

  20. DavidAckerman1651 –

  21. Renee22 –

    🙏🙏

  22. Jeffrey32 –

    Peptides are great

  23. Allison15 –

    No complaints!

  24. ilowery –

    Delivery was quick and packaged with care.

  25. Erica42 –

    Heard about this from podcast – Feel like peptides are the way of the future! I researched and thought this one was a good bet. 1st time orderer.

  26. Shane 1234 –

    Consistent quality

  27. MatthewC121 –

    Good

  28. Michael48 –

    acceptable, but I’ve had smoother orders before.

  29. DeborahD22 –

    Good experience overaall, would recommend.

  30. MargaretQ11 –

    Consistent results, seems like quality, appreciate it.

  31. ambermorgan –

    No issues w it

  32. Mark69 –

    THIS SUPPLIER NEVER DISAPPOINTS. VERY PLEASED WITH THIS PEPTIDE.

  33. CynthiaP112 –

    Good packaging

  34. knightfrank –

    Peptide is good, though price could be better.

  35. Christopher56 –

    @ Raw amino team, Provide more data pls

  36. Maverick –

    Product arrived exactly as expected, well packaged.

  37. Peter9 –

    Great produt

  38. ARMENIA22 –

    Thx

  39. JJ22 –

    Too soon to share lab results but got peptides in 2 days and got emails the entire process. Used welcome discount – sign up for the extra 10% or whatever it was off your first order which I appreciated, thanks raw amino

  40. xsmith –

  41. johnsonkevin –

  42. rnelson –

    Including bacteriostatic H20 for high orders is good touch thanks

  43. susanbeck –

    ⭐⭐⭐⭐⭐

  44. SamanthaJ1 –

    Outstanding purity.

  45. DeborahD –

  46. DavidB12 –

  47. Hal2000 –

    Premium

  48. anthonyjenkins –

  49. anthonyjenkins –

    very reliable supplier, always consistent.

  50. tina4422 –

  51. M90 –

  52. Skyline88 –

    Great quality, will order again.

  53. David7481 –

  54. thomas_jones –

  55. russell_jones –

  56. chelsea_bowman –

  57. Timothy88 –

  58. JJ93 –

  59. michael_livingston –

  60. david60 –

    Pleased with this

  61. David283 –

  62. Michael P. –

  63. Kimberly678 –

  64. DavidA1 –

    Good

  65. M9011 –

  66. Ashley55 –

  67. JacquelineP31 –

    Perfecto

  68. Ashley551 –

    Shipping was super fast! Came on time and as promised, no issues. I will keep ordering from here and see how results show up in the research.

Only logged in customers may leave a review.

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